Our White Papers
Dec 17, 2024
Lyophilization has long been a cornerstone of reagent stabilization, particularly in molecular diagnostics (MDx). Evik Diagnostics, with years of expertise and know-how in producing lyophilized reagent beads (lyo-beads), continues to refine this technology to meet evolving diagnostic demands. While traditional lyophilized reagent cakes (lyo-cakes) have been commonly used, lyo-beads offer distinct advantages, particularly in terms of performance, cost-effectiveness, scalability and quality control (QC). This paper presents the key features and benefits of lyo-beads compared to lyo-cakes, emphasizing their role in enhancing diagnostic efficiency and reliability...
Nov 6, 2024
A major challenge in the development of new laboratory diagnostic tests is in stabilizing the formulation. The formulations used in diagnostic testing are complex, containing active components like proteins, enzymes, antibodies, and even magnetic particles. In addition to these active ingredients, other components like buffers, salts, co-solvents, stabilizers, and excipients are commonly included to optimize performance and provide stability to the active ingredients. Despite the best efforts of Research and Development scientists, the long-term stability of these formulations is almost always limited. As such, organizations looking to scale production of diagnostic products have a few choices...
Aug 22, 2024
Lyophilization Brings Shelf-Stable Reagents to Point-of-Care Diagnostics
The advent of point-of-care (POC) and point-of-need (PON) testing allows users to rapidly receive in vitro diagnostic (IVD) test results without a centralized laboratory testing location. A challenge facing this industry is that the reagents necessary for diagnostic testing frequently have short shelf lives when stored at ambient, or even refrigerated, temperatures.
Additionally, these reagents would typically require cold-chain shipping and then storage at low, and, in some cases, ultra-low temperatures. Because POC and PON testing are intended to be...
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